- Bahia hairy dwarf porcupine
Sphiggurus insidiosus
- Mexican hairy dwarf porcupine
Sphiggurus mexicanus
- short-tailed spotted cuscus
Spilocuscus maculatus
- black-spotted cuscus
Spilocuscus rufoniger
- spinner dolphin
Stenella longirostris
- little Celebes cuscus
Strigocuscus celebensis
- little yellow-shouldered bat
Sturnira lilium
- white-toothed pygmy shrew
Suncus etruscus
- climbing shrew
Suncus megalura
- southern blossom bat
Syconycteris australis
- Audubon's cottontail
Sylvilagus audubonii
- eastern cottontail
Sylvilagus floridanus
- siamang
Symphalangus syndactylus